13 research outputs found
Oral mucosal melanoma: a malignant trap
Oral mucosal melanomas are highly malignant tumors. The 'chameleonic' presentation of a mainly asymptomatic condition, the rarity of these lesions, the poor prognosis and the necessity of a highly specialized treatment are factors that should be seriously considered by the involved health provider. We present the case of a 75-year-old man who was referred to the Ear, Nose and Throat department. His symptoms were voice alteration and saliva drooling, progressively worsening during the last few weeks. The absence of pain was the reason for the delay of seeking medical care. The diagnosis was an oversized oral melanoma. This is an example of how the time of diagnosis and the evolution of a disease could be seriously influenced by patient's behavior. Melanomas arising from oral mucosa have poor prognosis unless they are discovered and treated early. The vigilance of the physicians is necessary to have success in this difficult task
Osteoid osteoma of the ethmoid bone associated with dacryocystitis
BACKGROUND: Osteoid osteomas (OO) are small, benign osteoblastic lesions. Ethmoid bone OO has been very rarely reported so far. CASE PRESENTATION: We report a case of a 16-year-old boy suffering from persistent epiphora and a mild pain in the area of median canthus, due to a bone density mass within the right ethmoid air cells extending to the ipsilateral right orbit. The mass was removed via an external ethmoidectomy approach. Histopathologic examination of the specimen set the diagnosis of OO. One year after the operation the patient is free of symptoms, while no recurrence occurred. CONCLUSION: A case of ethmoid bone OO associated with dacryocystitis is reported. Although benign and rare, OO should be considered in differential diagnosis of the ethmoid bone osteoblastic lesions
Ectopic internal carotid artery presenting as an oropharyngeal mass
Ectopic internal carotid artery (ICA) is a very rare variation. The major congenital abnormalities of the ICA can be classified as agenesis, aplasia and hypoplasia, and they can be unilateral or bilateral. Anomalies of the neck artery may be vascular neoplasms or ectopic position. Carotid angiograms provide absolute confirmation of an aberrant carotid artery, while EcoColorDoppler (ECD) gives also important information about the evaluation of carotid vassels. Nevertheless Computed Tomography (CT) and Magnetic Resonance Imaging (MRI) of the neck provide spatial information about the adjacent pharyngeal anatomy and are less invasive than angiogram. Injuries to the ICA during simple pharyngeal surgical procedures can be catastrophic due to the risk of massive bleeding. We report a case of a 56 year-old male patient suffering from dysphagia associated with aberrant ICA manifesting itself as a pulsative protruding of the left lateral wall of the oropharynx
Συμβολή στην αντιμετώπιση των παραμόρφωσεων των πλάγιων χονδρών της μύτης
We have used this method on 11 patients who suffered from severe inspiratory nasal obstruction caused by atrophic ULCs. In comparison with other techniques, our technique has the advantage of preserving caudal portion of the lateral crura, which is essential for alar support.Παρουσιάζονται 11 περιστατικά με παραμόρφωση στους πλάγιους χόνδρους της μύτης. Εκτίθεται αναλυτικά η εφαρμοσθείσα σπό εμάς πρωτότυπη εγχειρητική τεχνική με τις παραλλαγές της για την αντιμετώπιση των παραμορφώσεων αυτών. Γίνεται δε ανιτκειμενική επιβεβαίωση των αποτελεσμάτων της τεχνικής μας με ρινομανομετρικό έλεγχο
Atopy does not affect the frequency of adenotonsillar hypertrophy and sleep apnoea in children who snore
AimViral respiratory infections and atopy have been implicated in the
pathogenesis of adenotonsillar hypertrophy and obstructive sleep apnoea
(OSA), but the role of atopy is controversial. We aimed to test our
hypothesis that atopy, expressed as physician-diagnosed eczema, was
associated with adenotonsillar hypertrophy and OSA among children who
snored.
MethodsData on children who snored and were referred for polysomnography
were reviewed. The primary outcome measures were adenotonsillar
hypertrophy and OSA.
ResultsWe analysed data on 855 children with a mean age (standard
deviation) of 6.3 (+/- 2.5) years and median obstructive apnoea-hypopnea
index of 2.1 episodes per hour. Of the 855 subjects, 133 (15.6%) had
physician-diagnosed eczema, 591 (69.1%) had adenoidal hypertrophy, 605
(70.8%) had tonsillar hypertrophy, 219 (25.6%) were obese and 470
(55%) had OSA. Eczema was not related to adenoidal or tonsillar
hypertrophy after adjustment for gender and age, with odds ratios (OR)
of 1.00 (95% confidence interval 0.67-1.49; p=0.98) and 0.88 (95%
confidence interval 0.59-1.32; p=0.54), respectively. Similarly, eczema
did not affect OSA frequency after adjustment for adenoidal and
tonsillar hypertrophy, obesity, gender and age, with an adjusted OR of
0.82 (0.56-1.21; p=0.32).
ConclusionsAtopy was not related to adenotonsillar hypertrophy or OSA in
children who snore
Herpes viruses and human papilloma virus in nasal polyposis and controls
ABSTRACT INTRODUCTION: Chronic rhinosinusitis with nasal polyps is a multifactorial disease entity with an unclear pathogenesis. Contradictory data exist in the literature on the potential implication of viral elements in adult patients with chronic rhinosinusitis. OBJECTIVE: To compare the prevalence of human herpes viruses (1-6) and Human Papilloma Virus in adult patients with chronic rhinosinusitis with nasal polyps and healthy controls. METHODS: Viral DNA presence was evaluated by real-time polymerase chain reaction application to nasal polyps specimens from 91 chronic rhinosinusitis with nasal polyps patients and nasal turbinate mucosa from 38 healthy controls. RESULTS: Epstein-Barr virus positivity was higher in nasal polyps (24/91; 26.4%) versus controls (4/38; 10.5%), but the difference did not reach significance (p = 0.06). Human herpes virus-6 positivity was lower in nasal polyps (13/91; 14.29%) versus controls (10/38; 26.32%,p = 0.13). In chronic rhinosinusitis with nasal polyps group, 1 sample was herpes simplex virus-1-positive (1/91; 1.1%), and another was cytomegalovirus-positive (1/91; 1.1%), versus none in controls. No sample was positive for herpes simplex virus-2, varicella-zoster virus, high-risk-human papilloma viruses (16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59) and low-risk-human papilloma viruses (6, 11). CONCLUSION: Differences in Epstein-Barr virus and human herpes virus-6 positivity among patients with chronic rhinosinusitis with nasal polyps and healthy controls are not statistically significant, weakening the likelihood of their implication in chronic rhinosinusitis with nasal polyps pathogenesis